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New AI-powered tests aim to speed up endometriosis diagnosis

Created at 5 Sep · 1:26 PM1 source↑ Market-relevant
IN SHORT

Endometriosis, a painful condition affecting 1 in 10 women, often takes years to diagnose. New AI-driven tests developed outside the U.S. show promise in detecting the disease earlier, potentially reducing diagnostic delays.

Key Numbers

1 in 10women affected by endometriosis worldwide
two to three weeksEndotest results availability

Who's Involved

Zoë Armstrong
31-year-old patient diagnosed with endometriosis after years of symptoms
Dr. Drorit Or
Mount Sinai West doctor discussing endometriosis symptoms and treatment
Dr. Megan Billow
Cleveland Clinic doctor explaining reasons for delayed endometriosis diagnosis
Dr. Mark Noar
Founder of EndoSure, developing diagnostic test for endometriosis
Dr. Andrew Spiers
Ziwig doctor discussing the Endotest diagnostic pathway

↳ Why This Matters

The development of new diagnostic tools, particularly those leveraging AI and advanced biological analysis, could significantly reduce the prolonged suffering and diagnostic delays experienced by millions of women with endometriosis, improving their quality of life and enabling timely treatment.

Key facts

  • Endometriosis, a condition where uterine-like tissue grows outside the uterus, affects 1 in 10 women globally.
  • Diagnosis can be delayed by a decade or more due to normalized period pain and overlapping symptoms.
  • New tests like EndoSure (electrical signals) and Endotest (saliva microRNAs) are available outside the U.S.
  • EndoSure is seeking FDA approval, while Endotest is becoming available in the U.S. through lab-developed pathways.
  • Treatments include pain relievers, hormone therapies, and surgical options.

Endometriosis, a chronic inflammatory disease affecting one in ten women worldwide, often eludes diagnosis for years due to normalized period pain and overlapping symptoms. Zoë Armstrong, a 31-year-old, shared her decade-long struggle before finally receiving a diagnosis. The condition can cause debilitating pain, fatigue, bloating, and infertility.

New diagnostic tests are emerging internationally, offering hope for earlier detection. EndoSure, a test measuring electrical signals in the gut, and Endotest, which analyzes saliva for microRNAs, are available in some countries. The UK's National Health Service is considering using these tests to expedite diagnosis. EndoSure is pursuing FDA approval in the U.S., while Endotest is being made available through certified laboratories.

U.S. medical experts acknowledge these tests could be valuable additions to the diagnostic process but emphasize they will not replace existing methods and may not fully address the issue of normalizing period pain. Treatment options for endometriosis include pain relievers, hormone therapies, and surgical interventions.

Frequently asked questions

Endometriosis is a condition where tissue similar to the lining of the uterus grows on other parts of the body, often causing chronic pain and inflammation.

Diagnosis is often delayed because period pain is normalized, symptoms overlap with other conditions, and not all healthcare providers have expertise in endometriosis.

New tests include EndoSure, which measures electrical signals in the gut, and Endotest, which analyzes saliva for microRNAs.

The tests are not yet FDA-approved in the U.S., but efforts are underway to make them available through different pathways.

What Happens Next

01EndoSure is submitting its application to the FDA for U.S. approval.
02Endotest is being made available to U.S. patients through lab-developed pathways.
03The UK's NHS will consider draft guidance recommending the use of EndoSure and Endotest.
CME Headlines
  • Risk Management and Monitoring Notice: Multi-Factor Authentication Updates - September 12
    3 Sep · 5:00 AM

How It Developed

Endometriosis can cause debilitating pain and takes years to diagnose.
New diagnostic tests are available in some countries but not yet approved in the U.S.
EndoSure, a half-hour test, measures electrical signals in the gut.
Endotest analyzes saliva samples for microRNAs.
The UK's NHS may use both tests for three years.
EndoSure is seeking FDA approval in the U.S.
Ziwig is making Endotest available in the U.S. via lab-developed pathways.
U.S. doctors see these tests as potentially helpful but not a complete solution.

Sources

T1
Endometriosis can elude diagnosis for years. What to know about the disease and new ways to find itAP News

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