Key facts
- A new gel developed by University of Nottingham scientists can repair and regenerate tooth enamel.
- The gel uses a bioinspired material that mimics natural proteins guiding enamel growth.
- The process, epitaxial mineralization, uses calcium and phosphate ions from saliva to grow new mineral.
- The regenerated enamel has been tested to withstand brushing, chewing, and acidic foods.
- The gel can also form an enamel-like layer on exposed dentine.
- The startup Mintech-Bio aims for a product launch next year.
Scientists from the University of Nottingham have developed a new gel capable of repairing and regenerating tooth enamel, a breakthrough that could significantly advance dental treatments. The gel, which is fluoride-free, works by mimicking the natural proteins involved in enamel formation during infancy. When applied, it forms a protective layer that draws calcium and phosphate ions from saliva to promote the growth of new mineral crystals in an organized manner, a process known as epitaxial mineralization. This allows the regenerated mineral to integrate with the existing tooth structure, restoring both the architecture and properties of healthy enamel.