Key facts
- Kratom, a plant-derived substance, is sold in various forms at gas stations, vape shops, and other stores.
- A concentrated byproduct, 7-hydroxymitragynine (7-OH), is considered a synthetic opioid and is more potent than morphine.
- Health agencies like the FDA are recommending control of 7-OH under the Controlled Substances Act due to addiction risks.
- Markwayne Mullin, who has equity in a company that could benefit from favorable policies, is noted as a potential ally for the kratom industry.
- Several jurisdictions have already banned or restricted kratom products and 7-OH.
The kratom industry is actively pursuing favorable policy outcomes, with potential allies emerging within political circles, including figures like Congressman Markwayne Mullin, who holds equity in a company that stands to benefit from such policies. This push occurs against a backdrop of increasing scrutiny from U.S. health agencies regarding kratom and its potent byproduct, 7-hydroxymitragynine (7-OH).
Health officials, including the FDA and HHS, are warning about the dangers of 7-OH, which is described as a concentrated form of kratom with opioid-like effects and a significant potential for abuse. The FDA has recommended scheduling 7-OH under the Controlled Substances Act, citing its potency, which can be up to 30 times greater than morphine, and the risk of addiction and drug-related symptoms. This has led to regulatory actions, with some states and localities already enacting bans or restrictions on kratom products and 7-OH.
Kratom, derived from the leaves of the Mitragyna speciosa tree, has been marketed as an all-natural herbal supplement for pain relief and anxiety. However, its active compounds, particularly mitragynine and 7-OH, have been linked to serious side effects, including seizures, heart problems, and organ damage. The substance's availability in gas stations, vape shops, and other retail outlets has raised concerns about a potential "fourth wave" of the opioid crisis. Wrongful death lawsuits have also been filed, highlighting the risks associated with kratom toxicity.