Foreign ministers from Saudi Arabia, Pakistan, Egypt and Turkiye, the R4, meet in Istanbul before being joined by the UK, France and Germany, the E3. Their first gathering in this format focuses on Iran and Yemen amid fears of fresh military escalation. Netanyahu campaigns on regime change in Tehran, while Trump signals possible new strikes and Tehran vows retaliation. Al Jazeera's Sinem Koseoglu reports. Subscribe to our channel: http://bit.ly/AJSubscribe Follow us on X : https://twitter.com/AJEnglish Find us on Facebook: https://www.facebook.com/aljazeera Check our website: http://www.aljazeera.com/ Check out our Instagram page: https://www.instagram.com/aljazeeraenglish/ Download AJE Mobile App: https://aje.news/AJEMobile #Türkiye #Istanbul #Iran #Yemen #R4 #E3 #StraitOfHormuz #Houthis #SaudiArabia #Pakistan #Egypt #UK #France #Germany #Netanyahu #Trump #OilPrices #ShippingCosts #MiddleEast