HomeEverythingEducation
Equities & FundsCrypto & Digital AssetsAI & TechnologyBusiness & CorporateUS Politics & PolicyGeopolitics & Global RiskMacro, Rates & FXCommodities & EnergyEuropean Politics & MarketsAsia-PacificReal Estate & Property
Story archiveAll categories
← All Stories

Jefferies downgrades Abivax to Hold after trial setback

Created at 3 Jun · 1:56 AM3 sources↑ Market-relevant3 events
IN SHORT

Jefferies downgraded Abivax from Buy to Hold and cut its price target by 44% following the emergence of rare cancer cases in the company's Phase 3 ulcerative colitis trial. Abivax shares fell over 40% in a single session.

✉Newsletter

PiQ Daily

Pick your topics. Get only what matters, on your cadence.

Key Numbers

44%price target reduction by Jefferies
40%share price drop in one session

Who's Involved

Jefferies
Analyst firm that downgraded Abivax
Abivax
Biopharmaceutical company facing trial setback

↳ Why This Matters

The emergence of safety concerns in a Phase 3 trial and subsequent analyst downgrades significantly impact investor confidence and the company's valuation, potentially affecting future drug development and market access.

Key facts

  • Jefferies downgraded Abivax from Buy to Hold.
  • Jefferies cut Abivax's price target by 44%.
  • Rare cancer cases emerged in Abivax's Phase 3 ulcerative colitis trial.
  • Abivax shares fell over 40% in one session.

Jefferies downgraded Abivax from a Buy rating to Hold, simultaneously reducing its price target by approximately 44%. This action follows the reported emergence of rare cancer cases during the company's Phase 3 clinical trial for ulcerative colitis. The news led to a significant drop in Abivax's stock value, with shares losing more than 40% of their worth in a single trading session. Wolfe Research also lowered its stock price target for Abivax due to safety concerns, reflecting a re-evaluation of the company's risk profile. An investigation into Abivax's officers and directors by SueWallSt is also noted.

Frequently asked questions

Abivax's stock fell over 40% after rare cancer cases were reported in its Phase 3 ulcerative colitis trial, leading to a downgrade by Jefferies.

Jefferies downgraded Abivax from a Buy rating to Hold.

Rare cancer cases have emerged during the company's Phase 3 trial for ulcerative colitis.

What Happens Next

01Further updates on the Abivax ulcerative colitis trial results.
02Potential regulatory actions or reviews by health authorities.
03Ongoing investigations into Abivax's officers and directors.

Get the newsletter.

Pick the topics you actually care about. We'll email when there's news worth your time, on the cadence you choose. Cancel any time from your account.

Cadence
CME Headlines
  • New Product Summary: Initial Listing of Fifty-Five (55) Single Stock Futures Contracts — Effective July 27, 2026
    27 Jul · 4:32 PM
  • New Product Summary: Initial Listing of Twenty-Two (22) Micro Single Stock Futures Contracts - Effective July 27, 2026
    27 Jul · 4:11 PM
  • Initial Listing of Additional Event Contract Swaps on Pro Golf Tournaments
    9 Jul · 9:41 AM

How It Developed

3 Jun · 5:37 PM
Wolfe Research cut Abivax's price target due to safety concerns, adding to Jefferies' earlier downgrade.
Investing.com via PiQSuite
3 Jun · 1:20 AM
Jefferies downgraded Abivax from Buy to Hold, cutting its price target by 44% after rare cancer cases emerged in its Phase 3 ulcerative colitis trial.
PRN | All News Releases via PiQSuite
2 Jun · 4:09 PM
New article highlights that cancer cases in Abivax's trial have raised questions about a potential takeover.
CNBC | US Top News and Analysis via PiQSuite

Sources

T1
Abivax Investigation Initiated: SueWallSt Investigates the Officers and Directors of Abivax (ABVX)m.piqsuite.com
T1
Biotech takeover target Abivax sinks over 43% as cancer cases cloud trial data for bowel disease drugm.piqsuite.com
T1
Wolfe Research cuts Abivax stock price target on safety concernsm.piqsuite.com

Related Stories

JPMorgan Hires Michael Flynn to Lead New Small-Cap Banking Business
8 Jul · 3:03 PM
SpaceX Analyst Maintains Neutral Stance Amid Wall Street Buy Frenzy
8 Jul · 10:00 AM
Memory Stocks Plunge as Year's Hottest Trade Unravels
8 Jul · 2:35 PM
HSBC downgrades EM equities on AI spending fears
8 Jul · 12:04 PM
Michael Burry Buys Flutter, DraftKings Shares on Prediction Market Threat
8 Jul · 9:51 PM