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Pioneering womb surgery corrects birth defect in unborn baby

Created at 3 Aug · 5:16 AM1 source↑ Market-relevant
IN SHORT

Doctors have successfully performed groundbreaking surgery on an unborn baby to correct gastroschisis, a condition where intestines grow outside the body. The procedure, part of a clinical trial, was performed on baby Theo while he was still inside his mother, Maisie Savage, at 26 weeks gestation.

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Key Numbers

1 in 3,000UK babies affected by gastroschisis annually
26 weeksGestation at time of surgery
5 monthsTheo's current age
Two yearsPotential IV nutritional feeding duration for complex cases without surgery
10%Mortality rate for complex gastroschisis cases

Who's Involved

Maisie Savage
Mother who underwent pioneering in-utero surgery
Theo
Baby successfully treated for gastroschisis in utero
Josh French
Father of baby Theo
Dr Michael Belfort
Clinical lead on the trial and surgeon at Texas Children's Hospital
Great Ormond Street Hospital
London hospital that referred the case and may perform future procedures
Texas Children's Hospital
US hospital where the pioneering surgery was performed

↳ Why This Matters

This pioneering surgery offers a new hope for babies born with severe gastroschisis, potentially reducing the need for extensive neonatal intensive care, multiple surgeries, and long-term feeding support, thereby improving outcomes and survival rates for a serious congenital defect.

Key facts

  • Doctors performed groundbreaking surgery on an unborn baby to correct gastroschisis.
  • The procedure took place while the baby, Theo, was still inside his mother, Maisie Savage, at 26 weeks gestation.
  • Theo is the third baby globally to benefit from this first-of-its-kind clinical trial.
  • The surgery involved partially exposing the mother's womb and using keyhole surgery to reposition the baby's organs.
  • Theo is now five months old and thriving, with his parents describing him as a 'miracle'.

Doctors have successfully performed groundbreaking surgery on an unborn baby to correct gastroschisis, a condition where the intestines grow outside the body due to improper belly button development. The procedure was carried out on five-month-old Theo while he was still inside his mother, Maisie Savage, at 26 weeks gestation.

Maisie, 29, and Theo's father, Josh French, 36, were initially unaware of the defect until a 20-week scan. After being prepared for the challenges of the condition by specialists at London's Great Ormond Street Hospital, they were referred to Texas Children's Hospital for a clinical trial led by Dr. Michael Belfort. The trial aims to repair complex gastroschisis before birth.

As part of the trial, Maisie first traveled to Belgium for a Botox injection to relax Theo's abdominal muscles. She then flew to Texas for the surgery, which involved partially exposing her womb and using keyhole techniques to gently push Theo's organs back inside his abdomen. The procedure was completed without complications, and Theo was born vaginally in February. He is now thriving, with his parents expressing immense relief and gratitude.

Dr. Belfort described the results as remarkable and expressed optimism about the future potential of in-utero surgery for various conditions, including cardiac and lung surgeries. Plans are in place for Great Ormond Street Hospital to potentially offer the procedure in the UK if the trial continues to be successful.

Frequently asked questions

Gastroschisis is a birth defect where the abdominal wall does not develop properly, causing the baby's intestines to grow outside the body.

The surgery was performed at Texas Children's Hospital in Houston, USA.

Theo is the third baby in the world to undergo this specific type of in-utero surgery for gastroschisis as part of a clinical trial.

The surgery was successful, with no complications reported. Baby Theo is now five months old and thriving.

What Happens Next

01Great Ormond Street Hospital aims to offer the procedure in the UK.
02Further research may explore in-utero cardiac and lung surgeries.

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Cadence

How It Developed

Baby Theo was diagnosed with gastroschisis during a 20-week scan.
Maisie Savage was referred to Texas Children's Hospital for a clinical trial.
Maisie received a Botox injection in Belgium to relax fetal abdominal muscles.
Theo underwent pioneering in-utero surgery at 26 weeks gestation in Texas.
Theo was born vaginally in February and is now thriving.
The surgical team reported zero complications during and after the fetal surgery.

Sources

T1
Woman has pioneering womb surgery to fix 'miracle' baby with intestines outside its bodyBBC News

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